Services Provided
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Structural Biology
I have several years of experience doing gene-to-structure protein crystallography in academia with industry applications. I can guide you towards efficient biochemical and biophysical methods to capture and understand ligand–protein interactions and transient protein–protein complexes.
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Structural Solutions
I have solved dozens of structures, including various lysosomal proteins, kinases, proteases, antibodies, and even de novo engineered proteins. I work with Helix BioStructures (Indiana, USA) to get the best diffraction datasets and corresponding structure solution models.
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Molecular Modeling
I regularly do small molecule and peptide docking to protein targets of interest. I can help you design and lead-optimize these molecules with structural insights and in vitro analyses. I use softwares like YASARA, BioSolveIT, & Schrödinger to enable these efforts.
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Scientific Analysis, Reports, & Presentations
Looking for an opportunity to review the primary literature in order to analyze and synthesize content for projects and programs? I can mine databases and present scientific findings that will facilitate hypotheses and augment benchwork efforts.
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In Vitro Assay Design & CRO Liaison
Need help figuring out what experiments are best fit to test a hypothesis or a series of preclinical assets? I am familiar with various biochemical and cellular approaches for preclinical testing. I can help support your communication with contract research organizations to help you get data that are reliable and reproducible, including from custom assays.
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Other Skills & Capabilities
Do you need assistance in project management, publication-quality figure/graph generation, experimental analysis or synthesis, grant applications, publication writing/editing, academic tutoring, or networking? I am flexible to help the cause and address the needs at hand.